BDBM50327491 2-(cyclopropylmethyl)-9-(1-isopropylpiperidin-4-yloxy)-2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,2-a]indol-1-one::CHEMBL1257728

SMILES: CC(C)N1CCC(CC1)Oc1ccc2n3CCCN(CC4CC4)C(=O)c3cc2c1

InChI Key: InChIKey=CQIVACKSIGNLEU-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327491 (2-(cyclopropylmethyl)-9-(1-isopropylpiperidin-4-yl...) Show SMILES CC(C)N1CCC(CC1)Oc1ccc2n3CCCN(CC4CC4)C(=O)c3cc2c1 Show InChI InChI=1S/C24H33N3O2/c1-17(2)25-12-8-20(9-13-25)29-21-6-7-22-19(14-21)15-23-24(28)26(16-18-4-5-18)10-3-11-27(22)23/h6-7,14-15,17-18,20H,3-5,8-13,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]-RAMH from human histamine H3 receptor				Bioorg Med Chem Lett 20: 5713-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.009 BindingDB Entry DOI: 10.7270/Q2571C7N
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327491 (2-(cyclopropylmethyl)-9-(1-isopropylpiperidin-4-yl...) Show SMILES CC(C)N1CCC(CC1)Oc1ccc2n3CCCN(CC4CC4)C(=O)c3cc2c1 Show InChI InChI=1S/C24H33N3O2/c1-17(2)25-12-8-20(9-13-25)29-21-6-7-22-19(14-21)15-23-24(28)26(16-18-4-5-18)10-3-11-27(22)23/h6-7,14-15,17-18,20H,3-5,8-13,16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
F Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Inverse agonist activity at human recombinant histamine H3 receptor assessed as effect on [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5713-7 (2010) Article DOI: 10.1016/j.bmcl.2010.08.009 BindingDB Entry DOI: 10.7270/Q2571C7N
					More data for this Ligand-Target Pair