BDBM50327502 (1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((2S,3S,4R,5S)-2,3,4,5,6-pentahydroxyhexyl)tetrahydro-1H-thiophenium chloride::CHEMBL1258529
SMILES: OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C[S@@+]1C[C@@H](O)[C@H](O)[C@H]1CO
InChI Key: InChIKey=CDSNPCIXSRDFFK-NFPDVKHNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Maltase-glucoamylase (Homo sapiens (Human)) | BDBM50327502 ((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Simon Fraser University Curated by ChEMBL | Assay Description Inhibition of human N-terminal maltase-glucoamylase | Bioorg Med Chem Lett 21: 6491-4 (2011) Article DOI: 10.1016/j.bmcl.2011.08.069 BindingDB Entry DOI: 10.7270/Q2Q81DHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Maltase-glucoamylase (Homo sapiens (Human)) | BDBM50327502 ((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Simon Fraser University Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal domain of maltase-glucoamylase after 60 mins by glucose oxidase assay | Bioorg Med Chem Lett 20: 5686-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.020 BindingDB Entry DOI: 10.7270/Q2WQ0411 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sucrase-isomaltase (Homo sapiens (Human)) | BDBM50327502 ((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 103 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Simon Fraser University Curated by ChEMBL | Assay Description Inhibition of human recombinant C-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6491-4 (2011) Article DOI: 10.1016/j.bmcl.2011.08.069 BindingDB Entry DOI: 10.7270/Q2Q81DHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sucrase-isomaltase (Homo sapiens (Human)) | BDBM50327502 ((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 302 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Simon Fraser University Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal Sucrase-isomaltase by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6491-4 (2011) Article DOI: 10.1016/j.bmcl.2011.08.069 BindingDB Entry DOI: 10.7270/Q2Q81DHZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acidic alpha-glucosidase (Rattus norvegicus) | BDBM50327502 ((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kinki University Curated by ChEMBL | Assay Description Inhibition of rat intestinal maltase | Bioorg Med Chem 19: 2015-22 (2011) Article DOI: 10.1016/j.bmc.2011.01.052 BindingDB Entry DOI: 10.7270/Q2J1044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat)) | BDBM50327502 ((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kinki University Curated by ChEMBL | Assay Description Inhibition of rat intestinal sucrase | Bioorg Med Chem 19: 2015-22 (2011) Article DOI: 10.1016/j.bmc.2011.01.052 BindingDB Entry DOI: 10.7270/Q2J1044C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat)) | BDBM50327502 ((1R,2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)-1-((...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kinki University Curated by ChEMBL | Assay Description Inhibition of rat intestinal isomaltase | Bioorg Med Chem 19: 2015-22 (2011) Article DOI: 10.1016/j.bmc.2011.01.052 BindingDB Entry DOI: 10.7270/Q2J1044C | |||||||||||
More data for this Ligand-Target Pair |