BDBM50327668 8-Bromo-11H-dibenzo[b,e]azepine::CHEMBL1255819

SMILES: Brc1ccc2Cc3ccccc3N=Cc2c1

InChI Key: InChIKey=NOVSJLUARMRDQL-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50327668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50327668 (8-Bromo-11H-dibenzo[b,e]azepine | CHEMBL1255819) Show SMILES Brc1ccc2Cc3ccccc3N=Cc2c1 |c:13| Show InChI InChI=1S/C14H10BrN/c15-13-6-5-10-7-11-3-1-2-4-14(11)16-9-12(10)8-13/h1-6,8-9H,7H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in T-REx-HEK293 cells assessed as increase of intracellular calcium level by FDSS assay				J Med Chem 53: 7011-20 (2010) Article DOI: 10.1021/jm100477n BindingDB Entry DOI: 10.7270/Q2474B2T
					More data for this Ligand-Target Pair