BindingDB PrimarySearch

BDBM50327945 (1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-butyl)-2,6,10,17-tetraoxa-tricyclo[11.3.1.1'1,5']octadecane-7,11-dione::CHEMBL1258349

SMILES: OC[C@H]1CC(=O)O[C@@H]2C[C@@H](CCCCc3ccccc3)O[C@@]3(CCC[C@H](CC(=O)O1)O3)C2

InChI Key: InChIKey=WUXPTIWFTBYPCX-CGRXCATRSA-N

Data: 8 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50327945
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50327945 ((1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-buty...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of [3H]PDBu binding to PKC delta C1B peptide				Bioorg Med Chem Lett 20: 6064-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.051 BindingDB Entry DOI: 10.7270/Q2FJ2H04
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50327945 ((1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-buty...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of [3H]PDBu binding to PKCtheta C1B peptide				Bioorg Med Chem Lett 20: 6064-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.051 BindingDB Entry DOI: 10.7270/Q2FJ2H04
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, eta (Homo sapiens (Human))	BDBM50327945 ((1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-buty...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of [3H]PDBu binding to PKCeta C1B peptide				Bioorg Med Chem Lett 20: 6064-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.051 BindingDB Entry DOI: 10.7270/Q2FJ2H04
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM50327945 ((1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-buty...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of [3H]PDBu binding to PKCepsilon C1B peptide				Bioorg Med Chem Lett 20: 6064-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.051 BindingDB Entry DOI: 10.7270/Q2FJ2H04
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50327945 ((1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-buty...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of [3H]PDBu binding to PKC gamma C1A peptide				Bioorg Med Chem Lett 20: 6064-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.051 BindingDB Entry DOI: 10.7270/Q2FJ2H04
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50327945 ((1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-buty...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of [3H]PDBu binding to PKC alpha C1A peptide				Bioorg Med Chem Lett 20: 6064-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.051 BindingDB Entry DOI: 10.7270/Q2FJ2H04
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50327945 ((1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-buty...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of [3H]PDBu binding to PKC beta C1A peptide				Bioorg Med Chem Lett 20: 6064-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.051 BindingDB Entry DOI: 10.7270/Q2FJ2H04
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50327945 ((1R,3R,5R,9R,13R)-9-Hydroxymethyl-3-(4-phenyl-buty...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Curated by ChEMBL					Assay Description Inhibition of [3H]PDBu binding to PKC delta C1A peptide				Bioorg Med Chem Lett 20: 6064-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.051 BindingDB Entry DOI: 10.7270/Q2FJ2H04
Kyoto University Curated by ChEMBL					More data for this Ligand-Target Pair