BDBM50328112 CHEMBL1257777::N-(2-Methoxybenzyl)-2,2-dimethyl-5-morpholin-4-yl-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine

SMILES: COc1ccccc1CNc1ncnc2c1sc1nc(N3CCOCC3)c3CCC(C)(C)Cc3c21

InChI Key: InChIKey=PJSHXKQUDQRRIZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50328112 (CHEMBL1257777 | N-(2-Methoxybenzyl)-2,2-dimethyl-5...) Show SMILES COc1ccccc1CNc1ncnc2c1sc1nc(N3CCOCC3)c3CCC(C)(C)Cc3c21 Show InChI InChI=1S/C27H31N5O2S/c1-27(2)9-8-18-19(14-27)21-22-23(35-26(21)31-25(18)32-10-12-34-13-11-32)24(30-16-29-22)28-15-17-6-4-5-7-20(17)33-3/h4-7,16H,8-15H2,1-3H3,(H,28,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of PDE4B1 expressed in yeast				J Med Chem 53: 6912-22 (2010) Article DOI: 10.1021/jm100524j BindingDB Entry DOI: 10.7270/Q2J966K2
					More data for this Ligand-Target Pair