BDBM50328113 1,1-Dimethyl-4-morpholin-4-yl-N7-(2-morpholin-4-ylethyl)-2,3-dihydro-1H-cyclopenta[4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-7-amine::CHEMBL1258469

SMILES: CC1(C)CCc2c1c1c(nc2N2CCOCC2)sc2c(NCCN3CCOCC3)ncnc12

InChI Key: InChIKey=JCJLPYMKWAKRDW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50328113 (1,1-Dimethyl-4-morpholin-4-yl-N7-(2-morpholin-4-yl...) Show SMILES CC1(C)CCc2c1c1c(nc2N2CCOCC2)sc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C24H32N6O2S/c1-24(2)4-3-16-18(24)17-19-20(33-23(17)28-22(16)30-9-13-32-14-10-30)21(27-15-26-19)25-5-6-29-7-11-31-12-8-29/h15H,3-14H2,1-2H3,(H,25,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	274	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of PDE4B1 expressed in yeast				J Med Chem 53: 6912-22 (2010) Article DOI: 10.1021/jm100524j BindingDB Entry DOI: 10.7270/Q2J966K2
					More data for this Ligand-Target Pair