BDBM50328116 CHEMBL1258689::N5-Benzyl-N5,2,2-Trimethyl-N-(2-morpholin-4-ylethyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]isoquinolin-8-amine

SMILES: CN(Cc1ccccc1)c1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2CC(C)(C)CCc12

InChI Key: InChIKey=FEWVTSJMUVJBFL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50328116 (CHEMBL1258689 | N5-Benzyl-N5,2,2-Trimethyl-N-(2-mo...) Show SMILES CN(Cc1ccccc1)c1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2CC(C)(C)CCc12 Show InChI InChI=1S/C29H36N6OS/c1-29(2)10-9-21-22(17-29)23-24-25(26(32-19-31-24)30-11-12-35-13-15-36-16-14-35)37-28(23)33-27(21)34(3)18-20-7-5-4-6-8-20/h4-8,19H,9-18H2,1-3H3,(H,30,31,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	865	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of PDE4B1 expressed in yeast				J Med Chem 53: 6912-22 (2010) Article DOI: 10.1021/jm100524j BindingDB Entry DOI: 10.7270/Q2J966K2
					More data for this Ligand-Target Pair