BDBM50328118 5-Morpholin-4-yl-N-(2-morpholin-4-ylethyl)-1,4-dihydro-2Hpyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8-amine::CHEMBL1258238

SMILES: C(CN1CCOCC1)Nc1ncnc2c1sc1nc(N3CCOCC3)c3COCCc3c21

InChI Key: InChIKey=IAASVKRMFFCTBS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50328118 (5-Morpholin-4-yl-N-(2-morpholin-4-ylethyl)-1,4-dih...) Show SMILES C(CN1CCOCC1)Nc1ncnc2c1sc1nc(N3CCOCC3)c3COCCc3c21 Show InChI InChI=1S/C22H28N6O3S/c1-8-31-13-16-15(1)17-18-19(32-22(17)26-21(16)28-6-11-30-12-7-28)20(25-14-24-18)23-2-3-27-4-9-29-10-5-27/h14H,1-13H2,(H,23,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of PDE4B1 expressed in yeast				J Med Chem 53: 6912-22 (2010) Article DOI: 10.1021/jm100524j BindingDB Entry DOI: 10.7270/Q2J966K2
					More data for this Ligand-Target Pair