BDBM50328119 2,2,3-Trimethyl-5-morpholin-4-yl-N-(2-morpholin-4-ylethyl)-1,2,3,4-tetrahydropyrimido[4',5':4,5]thieno[2,3-c]-2,7-naphthyridin-8-amine::CHEMBL1258239

SMILES: CN1Cc2c(CC1(C)C)c1c(nc2N2CCOCC2)sc2c(NCCN3CCOCC3)ncnc12

InChI Key: InChIKey=IUXAQCNYBMAYCZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50328119 (2,2,3-Trimethyl-5-morpholin-4-yl-N-(2-morpholin-4-...) Show SMILES CN1Cc2c(CC1(C)C)c1c(nc2N2CCOCC2)sc2c(NCCN3CCOCC3)ncnc12 Show InChI InChI=1S/C25H35N7O2S/c1-25(2)14-17-18(15-30(25)3)23(32-8-12-34-13-9-32)29-24-19(17)20-21(35-24)22(28-16-27-20)26-4-5-31-6-10-33-11-7-31/h16H,4-15H2,1-3H3,(H,26,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of PDE4B1 expressed in yeast				J Med Chem 53: 6912-22 (2010) Article DOI: 10.1021/jm100524j BindingDB Entry DOI: 10.7270/Q2J966K2
					More data for this Ligand-Target Pair