BDBM50328250 4-(2-aminothiazol-4-yl)-7-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)thiazol-2-ylthio)-2H-chromen-2-one::CHEMBL1258481

SMILES: Nc1nc(cs1)-c1cc(=O)oc2cc(Sc3ncc(s3)C(O)(C(F)(F)F)C(F)(F)F)ccc12

InChI Key: InChIKey=RWPZJWJYQIQHOF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malonyl-CoA decarboxylase (Homo sapiens (Human))	BDBM50328250 (4-(2-aminothiazol-4-yl)-7-(5-(1,1,1,3,3,3-hexafluo...) Show SMILES Nc1nc(cs1)-c1cc(=O)oc2cc(Sc3ncc(s3)C(O)(C(F)(F)F)C(F)(F)F)ccc12 Show InChI InChI=1S/C18H9F6N3O3S3/c19-17(20,21)16(29,18(22,23)24)12-5-26-15(33-12)32-7-1-2-8-9(10-6-31-14(25)27-10)4-13(28)30-11(8)3-7/h1-6,29H,(H2,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MCD				Bioorg Med Chem Lett 20: 6088-92 (2010) Article DOI: 10.1016/j.bmcl.2010.08.047 BindingDB Entry DOI: 10.7270/Q2542NTX
					More data for this Ligand-Target Pair