BDBM50328251 1,1,1,3,3,3-hexafluoro-2-(2-(p-tolylthio)thiazol-5-yl)propan-2-ol::CHEMBL1258592

SMILES: Cc1ccc(Sc2ncc(s2)C(O)(C(F)(F)F)C(F)(F)F)cc1

InChI Key: InChIKey=MBQWATUSPVZDJW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malonyl-CoA decarboxylase (Homo sapiens (Human))	BDBM50328251 (1,1,1,3,3,3-hexafluoro-2-(2-(p-tolylthio)thiazol-5...) Show SMILES Cc1ccc(Sc2ncc(s2)C(O)(C(F)(F)F)C(F)(F)F)cc1 Show InChI InChI=1S/C13H9F6NOS2/c1-7-2-4-8(5-3-7)22-10-20-6-9(23-10)11(21,12(14,15)16)13(17,18)19/h2-6,21H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human MCD				Bioorg Med Chem Lett 20: 6088-92 (2010) Article DOI: 10.1016/j.bmcl.2010.08.047 BindingDB Entry DOI: 10.7270/Q2542NTX
					More data for this Ligand-Target Pair