BDBM50328398 (Z)-3-((3-methylazulen-1-yl)methylene)indolin-2-one::CHEMBL1257803

SMILES: Cc1cc(\C=C2/C(=O)Nc3ccccc23)c2cccccc12

InChI Key: InChIKey=VPBCZAHOASOEIJ-PDGQHHTCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50328398 ((Z)-3-((3-methylazulen-1-yl)methylene)indolin-2-on...) Show SMILES Cc1cc(\C=C2/C(=O)Nc3ccccc23)c2cccccc12 Show InChI InChI=1S/C20H15NO/c1-13-11-14(16-8-4-2-3-7-15(13)16)12-18-17-9-5-6-10-19(17)21-20(18)22/h2-12H,1H3,(H,21,22)/b18-12-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Technology Research Institute Curated by ChEMBL					Assay Description Inhibition of FLT3 by time resolved fluorescence method				Bioorg Med Chem Lett 20: 6129-32 (2010) Article DOI: 10.1016/j.bmcl.2010.08.025 BindingDB Entry DOI: 10.7270/Q2N29X51
					More data for this Ligand-Target Pair