BDBM50328401 (Z)-5-fluoro-3-((3-fluoroazulen-1-yl)methylene)indolin-2-one::CHEMBL1257921

SMILES: Fc1cc(\C=C2/C(=O)Nc3ccc(F)cc23)c2cccccc12

InChI Key: InChIKey=UAPISUASGFYDRE-PXNMLYILSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50328401 ((Z)-5-fluoro-3-((3-fluoroazulen-1-yl)methylene)ind...) Show SMILES Fc1cc(\C=C2/C(=O)Nc3ccc(F)cc23)c2cccccc12 Show InChI InChI=1S/C19H11F2NO/c20-12-6-7-18-15(10-12)16(19(23)22-18)8-11-9-17(21)14-5-3-1-2-4-13(11)14/h1-10H,(H,22,23)/b16-8-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Technology Research Institute Curated by ChEMBL					Assay Description Inhibition of FLT3 by time resolved fluorescence method				Bioorg Med Chem Lett 20: 6129-32 (2010) Article DOI: 10.1016/j.bmcl.2010.08.025 BindingDB Entry DOI: 10.7270/Q2N29X51
					More data for this Ligand-Target Pair