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BDBM50328470 5-(Dimethylamino)-N-(3-{4-[6-({[5-(dimethylamino)-1-naphthyl]-sulfonyl}amino)hexyl]piperazin-1-yl}-4-methoxyphenyl)naphthalene-1-sulfonamide::CHEMBL1256258

SMILES: COc1ccc(NS(=O)(=O)c2cccc3c(cccc23)N(C)C)cc1N1CCN(CCCCCCNS(=O)(=O)c2cccc3c(cccc23)N(C)C)CC1

InChI Key: InChIKey=XMJHQAKLGNJANW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328470   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50328470
PNG
(5-(Dimethylamino)-N-(3-{4-[6-({[5-(dimethylamino)-...)
Show SMILES COc1ccc(NS(=O)(=O)c2cccc3c(cccc23)N(C)C)cc1N1CCN(CCCCCCNS(=O)(=O)c2cccc3c(cccc23)N(C)C)CC1
Show InChI InChI=1S/C41H52N6O5S2/c1-44(2)36-18-10-16-34-32(36)14-12-20-40(34)53(48,49)42-24-8-6-7-9-25-46-26-28-47(29-27-46)38-30-31(22-23-39(38)52-5)43-54(50,51)41-21-13-15-33-35(41)17-11-19-37(33)45(3)4/h10-23,30,42-43H,6-9,24-29H2,1-5H3
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Article
PubMed
 554n/an/an/an/an/an/an/an/a



Universidad Complutense deMadrid

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells

J Med Chem 53: 7095-106 (2010)


Article DOI: 10.1021/jm1007177
BindingDB Entry DOI: 10.7270/Q2445MQ0
More data for this
Ligand-Target Pair