BDBM50328531 3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imidazol-2-yl]-pyrrolidin-1-yl}-2,2-dimethylpropan-1-one::CHEMBL1259069

SMILES: CC(C)(Cc1ccc(cc1)-c1ccccc1)C(=O)N1CCC[C@H]1c1nc(c[nH]1)-c1cccc(F)c1

InChI Key: InChIKey=RMEWBPGDAAPWCD-MHZLTWQESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328531   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50328531 (3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imid...) Show SMILES CC(C)(Cc1ccc(cc1)-c1ccccc1)C(=O)N1CCC[C@H]1c1nc(c[nH]1)-c1cccc(F)c1 |r| Show InChI InChI=1S/C30H30FN3O/c1-30(2,19-21-13-15-23(16-14-21)22-8-4-3-5-9-22)29(35)34-17-7-12-27(34)28-32-20-26(33-28)24-10-6-11-25(31)18-24/h3-6,8-11,13-16,18,20,27H,7,12,17,19H2,1-2H3,(H,32,33)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PrCP by FRET				J Med Chem 53: 7251-63 (2010) Article DOI: 10.1021/jm101013m BindingDB Entry DOI: 10.7270/Q2QV3MQR
					More data for this Ligand-Target Pair
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50328531 (3-(Biphenyl-4-yl)-1-{2-[5-(3-fluorophenyl)-1H-imid...) Show SMILES CC(C)(Cc1ccc(cc1)-c1ccccc1)C(=O)N1CCC[C@H]1c1nc(c[nH]1)-c1cccc(F)c1 |r| Show InChI InChI=1S/C30H30FN3O/c1-30(2,19-21-13-15-23(16-14-21)22-8-4-3-5-9-22)29(35)34-17-7-12-27(34)28-32-20-26(33-28)24-10-6-11-25(31)18-24/h3-6,8-11,13-16,18,20,27H,7,12,17,19H2,1-2H3,(H,32,33)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PrCP by FRET in presence of 1% mouse serum albumin				J Med Chem 53: 7251-63 (2010) Article DOI: 10.1021/jm101013m BindingDB Entry DOI: 10.7270/Q2QV3MQR
					More data for this Ligand-Target Pair