BDBM50328569 3-(Biphenyl-4-yl)-1-{(2S)-2-[5-(3-methylphenyl)-1H-imidazol-2-yl]pyrrolidin-1-yl}propan-1-one::CHEMBL1259176

SMILES: Cc1cccc(c1)-c1c[nH]c(n1)C(=O)[C@@H]1CCCN1C(=O)CCc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=OHTAARMEESTGBR-MHZLTWQESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328569   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50328569 (3-(Biphenyl-4-yl)-1-{(2S)-2-[5-(3-methylphenyl)-1H...) Show SMILES Cc1cccc(c1)-c1c[nH]c(n1)C(=O)[C@@H]1CCCN1C(=O)CCc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C30H29N3O2/c1-21-7-5-10-25(19-21)26-20-31-30(32-26)29(35)27-11-6-18-33(27)28(34)17-14-22-12-15-24(16-13-22)23-8-3-2-4-9-23/h2-5,7-10,12-13,15-16,19-20,27H,6,11,14,17-18H2,1H3,(H,31,32)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PrCP by FRET				J Med Chem 53: 7251-63 (2010) Article DOI: 10.1021/jm101013m BindingDB Entry DOI: 10.7270/Q2QV3MQR
					More data for this Ligand-Target Pair