BDBM50328570 3-(Biphenyl-4-yl)-1-{2-[5-(3-chlorophenyl)-1H-imidazol-2-yl]-pyrrolidin-1-yl}propan-1-one::CHEMBL1259193

SMILES: Clc1cccc(c1)-c1c[nH]c(n1)C(=O)[C@@H]1CCCN1C(=O)CCc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=YRBNWLFNESEAEN-SANMLTNESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50328570 (3-(Biphenyl-4-yl)-1-{2-[5-(3-chlorophenyl)-1H-imid...) Show SMILES Clc1cccc(c1)-c1c[nH]c(n1)C(=O)[C@@H]1CCCN1C(=O)CCc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C29H26ClN3O2/c30-24-9-4-8-23(18-24)25-19-31-29(32-25)28(35)26-10-5-17-33(26)27(34)16-13-20-11-14-22(15-12-20)21-6-2-1-3-7-21/h1-4,6-9,11-12,14-15,18-19,26H,5,10,13,16-17H2,(H,31,32)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PrCP by FRET				J Med Chem 53: 7251-63 (2010) Article DOI: 10.1021/jm101013m BindingDB Entry DOI: 10.7270/Q2QV3MQR
					More data for this Ligand-Target Pair