BDBM50328788 (5-(4-chlorophenyl)-2-(2-methoxyphenyl)-7-methylimidazo[1,2-a]pyrimidin-6-yl)methanamine::CHEMBL1270560
SMILES: COc1ccccc1-c1cn2c(-c3ccc(Cl)cc3)c(CN)c(C)nc2n1
InChI Key: InChIKey=NIMUNPIVQZITIV-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50328788 ((5-(4-chlorophenyl)-2-(2-methoxyphenyl)-7-methylim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of human DPP4 after 15 mins by para-nitroaniline release assay | Bioorg Med Chem Lett 20: 6273-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.090 BindingDB Entry DOI: 10.7270/Q2J67H5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM50328788 ((5-(4-chlorophenyl)-2-(2-methoxyphenyl)-7-methylim...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of DPP9 after 15 mins by para-nitroaniline release assay | Bioorg Med Chem Lett 20: 6273-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.090 BindingDB Entry DOI: 10.7270/Q2J67H5R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase VIII (Homo sapiens (Human)) | BDBM50328788 ((5-(4-chlorophenyl)-2-(2-methoxyphenyl)-7-methylim...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Research and Development Curated by ChEMBL | Assay Description Inhibition of DPP8 after 15 mins by para-nitroaniline release assay | Bioorg Med Chem Lett 20: 6273-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.090 BindingDB Entry DOI: 10.7270/Q2J67H5R | |||||||||||
More data for this Ligand-Target Pair |