BDBM50328793 (5-(3-fluorophenyl)-2-(2-methoxyphenyl)-7-methylimidazo[1,2-a]pyrimidin-6-yl)methanamine::CHEMBL1270860

SMILES: COc1ccccc1-c1cn2c(-c3cccc(F)c3)c(CN)c(C)nc2n1

InChI Key: InChIKey=STJFISCADFIYRS-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50328793   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50328793 ((5-(3-fluorophenyl)-2-(2-methoxyphenyl)-7-methylim...) Show SMILES COc1ccccc1-c1cn2c(-c3cccc(F)c3)c(CN)c(C)nc2n1 Show InChI InChI=1S/C21H19FN4O/c1-13-17(11-23)20(14-6-5-7-15(22)10-14)26-12-18(25-21(26)24-13)16-8-3-4-9-19(16)27-2/h3-10,12H,11,23H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP4 after 15 mins by para-nitroaniline release assay				Bioorg Med Chem Lett 20: 6273-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.090 BindingDB Entry DOI: 10.7270/Q2J67H5R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50328793 ((5-(3-fluorophenyl)-2-(2-methoxyphenyl)-7-methylim...) Show SMILES COc1ccccc1-c1cn2c(-c3cccc(F)c3)c(CN)c(C)nc2n1 Show InChI InChI=1S/C21H19FN4O/c1-13-17(11-23)20(14-6-5-7-15(22)10-14)26-12-18(25-21(26)24-13)16-8-3-4-9-19(16)27-2/h3-10,12H,11,23H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of DPP9 after 15 mins by para-nitroaniline release assay				Bioorg Med Chem Lett 20: 6273-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.090 BindingDB Entry DOI: 10.7270/Q2J67H5R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50328793 ((5-(3-fluorophenyl)-2-(2-methoxyphenyl)-7-methylim...) Show SMILES COc1ccccc1-c1cn2c(-c3cccc(F)c3)c(CN)c(C)nc2n1 Show InChI InChI=1S/C21H19FN4O/c1-13-17(11-23)20(14-6-5-7-15(22)10-14)26-12-18(25-21(26)24-13)16-8-3-4-9-19(16)27-2/h3-10,12H,11,23H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of DPP8 after 15 mins by para-nitroaniline release assay				Bioorg Med Chem Lett 20: 6273-6 (2010) Article DOI: 10.1016/j.bmcl.2010.08.090 BindingDB Entry DOI: 10.7270/Q2J67H5R
					More data for this Ligand-Target Pair