BDBM50329368 1,1-bis(4-chlorophenyl)-4-(dimethylamino)butan-1-ol::CHEMBL1270616

SMILES: CN(C)CCCC(O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key: InChIKey=HLDRWGIUUGWICY-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50329368 (1,1-bis(4-chlorophenyl)-4-(dimethylamino)butan-1-o...) Show SMILES CN(C)CCCC(O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H21Cl2NO/c1-21(2)13-3-12-18(22,14-4-8-16(19)9-5-14)15-6-10-17(20)11-7-15/h4-11,22H,3,12-13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to Bcl-XL by NMR titration assay				Bioorg Med Chem Lett 20: 6587-91 (2010) Article DOI: 10.1016/j.bmcl.2010.09.033 BindingDB Entry DOI: 10.7270/Q2J103C3
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50329368 (1,1-bis(4-chlorophenyl)-4-(dimethylamino)butan-1-o...) Show SMILES CN(C)CCCC(O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H21Cl2NO/c1-21(2)13-3-12-18(22,14-4-8-16(19)9-5-14)15-6-10-17(20)11-7-15/h4-11,22H,3,12-13H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to Bcl-2 by NMR titration assay				Bioorg Med Chem Lett 20: 6587-91 (2010) Article DOI: 10.1016/j.bmcl.2010.09.033 BindingDB Entry DOI: 10.7270/Q2J103C3
					More data for this Ligand-Target Pair