BDBM50329383 4'-((4-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)phenoxy)methyl)biphenyl-4-carboxylic acid::CHEMBL1271331

SMILES: CN(C)CCCC(O)(c1ccccc1)c1ccc(OCc2ccc(cc2)-c2ccc(cc2)C(O)=O)cc1

InChI Key: InChIKey=DFHCZTWDKWGWLI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50329383 (4'-((4-(4-(dimethylamino)-1-hydroxy-1-phenylbutyl)...) Show SMILES CN(C)CCCC(O)(c1ccccc1)c1ccc(OCc2ccc(cc2)-c2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C32H33NO4/c1-33(2)22-6-21-32(36,28-7-4-3-5-8-28)29-17-19-30(20-18-29)37-23-24-9-11-25(12-10-24)26-13-15-27(16-14-26)31(34)35/h3-5,7-20,36H,6,21-23H2,1-2H3,(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Bcl-2 by fluorescence polarization assay				Bioorg Med Chem Lett 20: 6587-91 (2010) Article DOI: 10.1016/j.bmcl.2010.09.033 BindingDB Entry DOI: 10.7270/Q2J103C3
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