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BDBM50329386 4'-(2-chloro-5-(1-(4-chlorophenyl)-1-hydroxy-3-morpholinopropyl)phenethoxy)biphenyl-4-carboxylic acid::CHEMBL1269504

SMILES: OC(=O)c1ccc(cc1)-c1ccc(OCCc2cc(ccc2Cl)C(O)(CCN2CCOCC2)c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=CYNBHDONBLRMMT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50329386   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50329386
PNG
(4'-(2-chloro-5-(1-(4-chlorophenyl)-1-hydroxy-3-mor...)
Show SMILES OC(=O)c1ccc(cc1)-c1ccc(OCCc2cc(ccc2Cl)C(O)(CCN2CCOCC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C34H33Cl2NO5/c35-30-10-7-28(8-11-30)34(40,16-17-37-18-21-41-22-19-37)29-9-14-32(36)27(23-29)15-20-42-31-12-5-25(6-13-31)24-1-3-26(4-2-24)33(38)39/h1-14,23,40H,15-22H2,(H,38,39)
PDB

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UniProtKB/TrEMBL

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Similars
Article
PubMed
 220n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Bcl-2 by fluorescence polarization assay

Bioorg Med Chem Lett 20: 6587-91 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.033
BindingDB Entry DOI: 10.7270/Q2J103C3
More data for this
Ligand-Target Pair