BDBM50329494 5-isoxazoyl-Cha-Ile-(3-aminophenyl)-(4-[aminomethyl]piperidin-1-yl)methanone::CHEMBL1269139
SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)Nc1cccc(c1)C(=O)N1CCC(CN)CC1
InChI Key: InChIKey=JNVWQTNIDLAFGO-PTJQVGQKSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteinase-activated receptor 2 (Homo sapiens (Human)) | BDBM50329494 (5-isoxazoyl-Cha-Ile-(3-aminophenyl)-(4-[aminomethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium release | J Med Chem 53: 7428-40 (2010) Article DOI: 10.1021/jm100984y BindingDB Entry DOI: 10.7270/Q2W959F7 | |||||||||||
More data for this Ligand-Target Pair |