BDBM50329648 2,4,5-trifluorophenyl 9H-pyrido[3,4-b]indole-3-carboxylate::CHEMBL1270741

SMILES: Fc1cc(F)c(OC(=O)c2cc3c(cn2)[nH]c2ccccc32)cc1F

InChI Key: InChIKey=RFYCGFKOGLYZKJ-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50329648   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329648 (2,4,5-trifluorophenyl 9H-pyrido[3,4-b]indole-3-car...) Show SMILES Fc1cc(F)c(OC(=O)c2cc3c(cn2)[nH]c2ccccc32)cc1F Show InChI InChI=1S/C18H9F3N2O2/c19-11-6-13(21)17(7-12(11)20)25-18(24)15-5-10-9-3-1-2-4-14(9)23-16(10)8-22-15/h1-8,23H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha1beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329648 (2,4,5-trifluorophenyl 9H-pyrido[3,4-b]indole-3-car...) Show SMILES Fc1cc(F)c(OC(=O)c2cc3c(cn2)[nH]c2ccccc32)cc1F Show InChI InChI=1S/C18H9F3N2O2/c19-11-6-13(21)17(7-12(11)20)25-18(24)15-5-10-9-3-1-2-4-14(9)23-16(10)8-22-15/h1-8,23H	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	44.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha3beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329648 (2,4,5-trifluorophenyl 9H-pyrido[3,4-b]indole-3-car...) Show SMILES Fc1cc(F)c(OC(=O)c2cc3c(cn2)[nH]c2ccccc32)cc1F Show InChI InChI=1S/C18H9F3N2O2/c19-11-6-13(21)17(7-12(11)20)25-18(24)15-5-10-9-3-1-2-4-14(9)23-16(10)8-22-15/h1-8,23H	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha2beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329648 (2,4,5-trifluorophenyl 9H-pyrido[3,4-b]indole-3-car...) Show SMILES Fc1cc(F)c(OC(=O)c2cc3c(cn2)[nH]c2ccccc32)cc1F Show InChI InChI=1S/C18H9F3N2O2/c19-11-6-13(21)17(7-12(11)20)25-18(24)15-5-10-9-3-1-2-4-14(9)23-16(10)8-22-15/h1-8,23H	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	422	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha5beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-6/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329648 (2,4,5-trifluorophenyl 9H-pyrido[3,4-b]indole-3-car...) Show SMILES Fc1cc(F)c(OC(=O)c2cc3c(cn2)[nH]c2ccccc32)cc1F Show InChI InChI=1S/C18H9F3N2O2/c19-11-6-13(21)17(7-12(11)20)25-18(24)15-5-10-9-3-1-2-4-14(9)23-16(10)8-22-15/h1-8,23H	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha6beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair
GABA receptor alpha-4/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50329648 (2,4,5-trifluorophenyl 9H-pyrido[3,4-b]indole-3-car...) Show SMILES Fc1cc(F)c(OC(=O)c2cc3c(cn2)[nH]c2ccccc32)cc1F Show InChI InChI=1S/C18H9F3N2O2/c19-11-6-13(21)17(7-12(11)20)25-18(24)15-5-10-9-3-1-2-4-14(9)23-16(10)8-22-15/h1-8,23H	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Milwaukee Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from human recombinant GABAA alpha4beta3gamma2 receptor expressed in HEK cells by liquid scintillation counting				Bioorg Med Chem 18: 7548-64 (2010) Article DOI: 10.1016/j.bmc.2010.08.049 BindingDB Entry DOI: 10.7270/Q2G1613B
					More data for this Ligand-Target Pair