BDBM50330106 CHEMBL1271711::N-(5-(3-(pyridin-3-yl)-5-(trifluoromethyl)-1H-pyrazol-1-yl)pyrazin-2-yl)benzamide

SMILES: FC(F)(F)c1cc(nn1-c1cnc(NC(=O)c2ccccc2)cn1)-c1cccnc1

InChI Key: InChIKey=KLUBTBYLHVKGLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50330106 (CHEMBL1271711 | N-(5-(3-(pyridin-3-yl)-5-(trifluor...) Show SMILES FC(F)(F)c1cc(nn1-c1cnc(NC(=O)c2ccccc2)cn1)-c1cccnc1 Show InChI InChI=1S/C20H13F3N6O/c21-20(22,23)16-9-15(14-7-4-8-24-10-14)28-29(16)18-12-25-17(11-26-18)27-19(30)13-5-2-1-3-6-13/h1-12H,(H,25,27,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human Ephx2 after 30 mins by fluorescence polarization assay				Bioorg Med Chem Lett 20: 6379-83 (2010) Article DOI: 10.1016/j.bmcl.2010.09.095 BindingDB Entry DOI: 10.7270/Q2V69JT7
					More data for this Ligand-Target Pair