BDBM50330644 CHEMBL1277117::N-(4-tert-Butyl-benzyl)-2-(3-iodo-4-hydroxy-5-methoxyphenyl)acetamide

SMILES: COc1cc(CC(=O)NCc2ccc(cc2)C(C)(C)C)cc(I)c1O

InChI Key: InChIKey=LPMQHXZYYIFTOJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50330644 (CHEMBL1277117 | N-(4-tert-Butyl-benzyl)-2-(3-iodo-...) Show SMILES COc1cc(CC(=O)NCc2ccc(cc2)C(C)(C)C)cc(I)c1O Show InChI InChI=1S/C20H24INO3/c1-20(2,3)15-7-5-13(6-8-15)12-22-18(23)11-14-9-16(21)19(24)17(10-14)25-4/h5-10,24H,11-12H2,1-4H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium uptake				Bioorg Med Chem 18: 8092-105 (2010) Article DOI: 10.1016/j.bmc.2010.09.001 BindingDB Entry DOI: 10.7270/Q2Q81D98
					More data for this Ligand-Target Pair
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50330644 (CHEMBL1277117 | N-(4-tert-Butyl-benzyl)-2-(3-iodo-...) Show SMILES COc1cc(CC(=O)NCc2ccc(cc2)C(C)(C)C)cc(I)c1O Show InChI InChI=1S/C20H24INO3/c1-20(2,3)15-7-5-13(6-8-15)12-22-18(23)11-14-9-16(21)19(24)17(10-14)25-4/h5-10,24H,11-12H2,1-4H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [3H]RTX from rat TRPV1 expressed in CHO cells				Bioorg Med Chem 18: 8092-105 (2010) Article DOI: 10.1016/j.bmc.2010.09.001 BindingDB Entry DOI: 10.7270/Q2Q81D98
					More data for this Ligand-Target Pair