BDBM50330786 CHEMBL1277410::N-Methyl-3-phenyl-3-(6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-yloxy)propan-1-amine
SMILES: CNCCC(Oc1cccc2cc(OCCN3CCCC3)ccc12)c1ccccc1
InChI Key: InChIKey=YRQMTSHAIPAQIW-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50330786 (CHEMBL1277410 | N-Methyl-3-phenyl-3-(6-(2-(pyrroli...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]-N-R-methylhistamine from rat H3 receptor | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50330786 (CHEMBL1277410 | N-Methyl-3-phenyl-3-(6-(2-(pyrroli...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex | J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F | |||||||||||
More data for this Ligand-Target Pair |