BDBM50330787 4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol::CHEMBL1277411

SMILES: CNCCC(c1ccccc1)c1ccc(O)c2ccc(OCCN3CCCC3)cc12

InChI Key: InChIKey=ZXMRPSJTSMBYHQ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50330787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50330787 (4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...) Show SMILES CNCCC(c1ccccc1)c1ccc(O)c2ccc(OCCN3CCCC3)cc12 Show InChI InChI=1S/C26H32N2O2/c1-27-14-13-22(20-7-3-2-4-8-20)23-11-12-26(29)24-10-9-21(19-25(23)24)30-18-17-28-15-5-6-16-28/h2-4,7-12,19,22,27,29H,5-6,13-18H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of SERT				J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50330787 (4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...) Show SMILES CNCCC(c1ccccc1)c1ccc(O)c2ccc(OCCN3CCCC3)cc12 Show InChI InChI=1S/C26H32N2O2/c1-27-14-13-22(20-7-3-2-4-8-20)23-11-12-26(29)24-10-9-21(19-25(23)24)30-18-17-28-15-5-6-16-28/h2-4,7-12,19,22,27,29H,5-6,13-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-R-methylhistamine from human H3 receptor isolated from C6 cells				J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus (rat))	BDBM50330787 (4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...) Show SMILES CNCCC(c1ccccc1)c1ccc(O)c2ccc(OCCN3CCCC3)cc12 Show InChI InChI=1S/C26H32N2O2/c1-27-14-13-22(20-7-3-2-4-8-20)23-11-12-26(29)24-10-9-21(19-25(23)24)30-18-17-28-15-5-6-16-28/h2-4,7-12,19,22,27,29H,5-6,13-18H2,1H3	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from rat NET in rat cerebral cortex				J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50330787 (4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...) Show SMILES CNCCC(c1ccccc1)c1ccc(O)c2ccc(OCCN3CCCC3)cc12 Show InChI InChI=1S/C26H32N2O2/c1-27-14-13-22(20-7-3-2-4-8-20)23-11-12-26(29)24-10-9-21(19-25(23)24)30-18-17-28-15-5-6-16-28/h2-4,7-12,19,22,27,29H,5-6,13-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-N-R-methylhistamine from rat H3 receptor				J Med Chem 53: 7869-73 (2010) Article DOI: 10.1021/jm100666w BindingDB Entry DOI: 10.7270/Q2P84C4F
					More data for this Ligand-Target Pair