BDBM50330947 CHEMBL1277792::N-((3-Morpholinopyridin-4-yl)methyl)-6-(4-chlorophenyl)-pyrazine-2-carboxamide

SMILES: Clc1ccc(cc1)-c1cncc(n1)C(=O)NCc1ccncc1N1CCOCC1

InChI Key: InChIKey=XODADHNSUQUULV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50330947 (CHEMBL1277792 | N-((3-Morpholinopyridin-4-yl)methy...) Show SMILES Clc1ccc(cc1)-c1cncc(n1)C(=O)NCc1ccncc1N1CCOCC1 Show InChI InChI=1S/C21H20ClN5O2/c22-17-3-1-15(2-4-17)18-12-24-13-19(26-18)21(28)25-11-16-5-6-23-14-20(16)27-7-9-29-10-8-27/h1-6,12-14H,7-11H2,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant NaV1.8 expressed in HEK293 cells by conventional voltageclamp electrophysiology assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50330947 (CHEMBL1277792 | N-((3-Morpholinopyridin-4-yl)methy...) Show SMILES Clc1ccc(cc1)-c1cncc(n1)C(=O)NCc1ccncc1N1CCOCC1 Show InChI InChI=1S/C21H20ClN5O2/c22-17-3-1-15(2-4-17)18-12-24-13-19(26-18)21(28)25-11-16-5-6-23-14-20(16)27-7-9-29-10-8-27/h1-6,12-14H,7-11H2,(H,25,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair