BDBM50330950 CHEMBL1277699::N-(Pyridin-3-ylmethyl)-6-(4-chlorophenyl)-pyrazine-2-carboxamide

SMILES: Clc1ccc(cc1)-c1cncc(n1)C(=O)NCc1cccnc1

InChI Key: InChIKey=RTLCJBCGHVLAIU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50330950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type X alpha subunit (Mus musculus)	BDBM50330950 (CHEMBL1277699 | N-(Pyridin-3-ylmethyl)-6-(4-chloro...) Show SMILES Clc1ccc(cc1)-c1cncc(n1)C(=O)NCc1cccnc1 Show InChI InChI=1S/C17H13ClN4O/c18-14-5-3-13(4-6-14)15-10-20-11-16(22-15)17(23)21-9-12-2-1-7-19-8-12/h1-8,10-11H,9H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse NaV1.8 expressed in HEK293 cells by isotopic efflux assay				Bioorg Med Chem 18: 7816-25 (2010) Article DOI: 10.1016/j.bmc.2010.09.057 BindingDB Entry DOI: 10.7270/Q24B31KG
					More data for this Ligand-Target Pair