BDBM50330953 CHEMBL4159632

SMILES: NCc1cccc(c1)-c1cccc(NC(=O)c2ccccc2)c1

InChI Key: InChIKey=WGIKZSZDLXUEEA-UHFFFAOYSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM50330953 (CHEMBL4159632) Show SMILES NCc1cccc(c1)-c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C20H18N2O/c21-14-15-6-4-9-17(12-15)18-10-5-11-19(13-18)22-20(23)16-7-2-1-3-8-16/h1-13H,14,21H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.57E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Displacement of 19F[(S)-methyl 2-((2-(3-(trifluoromethoxy)phenylcarbamoyl)pyrrolidine-1-carboxamido)methyl)benzoate] from complement factor D (unknow...				ACS Med Chem Lett 9: 490-495 (2018) Article DOI: 10.1021/acsmedchemlett.8b00104 BindingDB Entry DOI: 10.7270/Q2K35X6P
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM50330953 (CHEMBL4159632) Show SMILES NCc1cccc(c1)-c1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C20H18N2O/c21-14-15-6-4-9-17(12-15)18-10-5-11-19(13-18)22-20(23)16-7-2-1-3-8-16/h1-13H,14,21H2,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Displacement of 19F[(S)-methyl 2-((2-(3-(trifluoromethoxy)phenylcarbamoyl)pyrrolidine-1-carboxamido)methyl)benzoate] from complement factor D (unknow...				ACS Med Chem Lett 9: 490-495 (2018) Article DOI: 10.1021/acsmedchemlett.8b00104 BindingDB Entry DOI: 10.7270/Q2K35X6P
					More data for this Ligand-Target Pair