BDBM50331082 CHEMBL1290361::N-(2-bromophenyl)-2-(4-(2-methyl-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)acetamide::cid_1462274

SMILES: Cc1nc2ccccc2n1C1CCN(CC(=O)Nc2ccccc2Br)CC1

InChI Key: InChIKey=WOSAORHVEAJOFC-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ubiquitin-conjugating enzyme E2 N (Homo sapiens (Human))	BDBM50331082 (CHEMBL1290361 | N-(2-bromophenyl)-2-(4-(2-methyl-1...) Show SMILES Cc1nc2ccccc2n1C1CCN(CC(=O)Nc2ccccc2Br)CC1 Show InChI InChI=1S/C21H23BrN4O/c1-15-23-19-8-4-5-9-20(19)26(15)16-10-12-25(13-11-16)14-21(27)24-18-7-3-2-6-17(18)22/h2-9,16H,10-14H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2X34VX0
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50331082 (CHEMBL1290361 | N-(2-bromophenyl)-2-(4-(2-methyl-1...) Show SMILES Cc1nc2ccccc2n1C1CCN(CC(=O)Nc2ccccc2Br)CC1 Show InChI InChI=1S/C21H23BrN4O/c1-15-23-19-8-4-5-9-20(19)26(15)16-10-12-25(13-11-16)14-21(27)24-18-7-3-2-6-17(18)22/h2-9,16H,10-14H2,1H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Konkuk University Curated by ChEMBL					Assay Description Inhibition of recombinant VEGFR2 after 1 hr by fluorescence polarization assay				Eur J Med Chem 45: 5420-7 (2010) Article DOI: 10.1016/j.ejmech.2010.09.002 BindingDB Entry DOI: 10.7270/Q2TX3FMZ
					More data for this Ligand-Target Pair
ubiquitin-conjugating enzyme E2 N (Homo sapiens (Human))	BDBM50331082 (CHEMBL1290361 | N-(2-bromophenyl)-2-(4-(2-methyl-1...) Show SMILES Cc1nc2ccccc2n1C1CCN(CC(=O)Nc2ccccc2Br)CC1 Show InChI InChI=1S/C21H23BrN4O/c1-15-23-19-8-4-5-9-20(19)26(15)16-10-12-25(13-11-16)14-21(27)24-18-7-3-2-6-17(18)22/h2-9,16H,10-14H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2SB4462
					More data for this Ligand-Target Pair
Bfl-1 (Mus musculus (Mouse))	BDBM50331082 (CHEMBL1290361 | N-(2-bromophenyl)-2-(4-(2-methyl-1...) Show SMILES Cc1nc2ccccc2n1C1CCN(CC(=O)Nc2ccccc2Br)CC1 Show InChI InChI=1S/C21H23BrN4O/c1-15-23-19-8-4-5-9-20(19)26(15)16-10-12-25(13-11-16)14-21(27)24-18-7-3-2-6-17(18)22/h2-9,16H,10-14H2,1H3,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q25D8Q92
					More data for this Ligand-Target Pair