BDBM50331093 CHEMBL4174337

SMILES: CC(C)[C@H](Nc1nccc(Nc2cccc(CN)c2)n1)C(O)=O

InChI Key: InChIKey=JHRWBDMLCKJMJG-AWEZNQCLSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement factor D (Homo sapiens (Human))	BDBM50331093 (CHEMBL4174337) Show SMILES CC(C)[C@H](Nc1nccc(Nc2cccc(CN)c2)n1)C(O)=O |r| Show InChI InChI=1S/C16H21N5O2/c1-10(2)14(15(22)23)21-16-18-7-6-13(20-16)19-12-5-3-4-11(8-12)9-17/h3-8,10,14H,9,17H2,1-2H3,(H,22,23)(H2,18,19,20,21)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Displacement of 19F[(S)-methyl 2-((2-(3-(trifluoromethoxy)phenylcarbamoyl)pyrrolidine-1-carboxamido)methyl)benzoate] from complement factor D (unknow...				ACS Med Chem Lett 9: 490-495 (2018) Article DOI: 10.1021/acsmedchemlett.8b00104 BindingDB Entry DOI: 10.7270/Q2K35X6P
					More data for this Ligand-Target Pair
Complement factor D (Homo sapiens (Human))	BDBM50331093 (CHEMBL4174337) Show SMILES CC(C)[C@H](Nc1nccc(Nc2cccc(CN)c2)n1)C(O)=O |r| Show InChI InChI=1S/C16H21N5O2/c1-10(2)14(15(22)23)21-16-18-7-6-13(20-16)19-12-5-3-4-11(8-12)9-17/h3-8,10,14H,9,17H2,1-2H3,(H,22,23)(H2,18,19,20,21)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Displacement of 19F[(S)-methyl 2-((2-(3-(trifluoromethoxy)phenylcarbamoyl)pyrrolidine-1-carboxamido)methyl)benzoate] from complement factor D (unknow...				ACS Med Chem Lett 9: 490-495 (2018) Article DOI: 10.1021/acsmedchemlett.8b00104 BindingDB Entry DOI: 10.7270/Q2K35X6P
					More data for this Ligand-Target Pair