BDBM50331163 1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)-4-ortho-tolylpyridin-2(1H)-one::CHEMBL1289718

SMILES: Cc1ccccc1-c1ccn(-c2ccc3n(CCN4CCCC4)ncc3c2)c(=O)c1

InChI Key: InChIKey=JVTVPKDCDLMSIW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50331163 (1-(1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazol-5-yl)-4...) Show SMILES Cc1ccccc1-c1ccn(-c2ccc3n(CCN4CCCC4)ncc3c2)c(=O)c1 Show InChI InChI=1S/C25H26N4O/c1-19-6-2-3-7-23(19)20-10-13-28(25(30)17-20)22-8-9-24-21(16-22)18-26-29(24)15-14-27-11-4-5-12-27/h2-3,6-10,13,16-18H,4-5,11-12,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	539	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AMRI Curated by ChEMBL					Assay Description Displacement of [3H]GW803430 from MCH-1 receptor expressed in CHO-K1 cells				Bioorg Med Chem Lett 20: 7020-3 (2010) Article DOI: 10.1016/j.bmcl.2010.09.037 BindingDB Entry DOI: 10.7270/Q2639PZR
					More data for this Ligand-Target Pair