BDBM50331273 3-(6-methyl-1H-indol-2-yl)-1H-indazole-6-carbonitrile::CHEMBL1289729

SMILES: Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cc(ccc12)C#N

InChI Key: InChIKey=VAJIEBPJVXNWST-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50331273 (3-(6-methyl-1H-indol-2-yl)-1H-indazole-6-carbonitr...) Show SMILES Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cc(ccc12)C#N Show InChI InChI=1S/C17H12N4/c1-10-2-4-12-8-16(19-14(12)6-10)17-13-5-3-11(9-18)7-15(13)20-21-17/h2-8,19H,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 20: 6998-7003 (2010) Article DOI: 10.1016/j.bmcl.2010.09.119 BindingDB Entry DOI: 10.7270/Q2JD4X29
					More data for this Ligand-Target Pair