BDBM50331315 (+/-)-3-(1,4-Dioxaspiro[4.5]decan-8-yl)-2,3,4,5-tetrahydro-1H-3-benzazepine-1,7-diol::CHEMBL1289732

SMILES: OC1CN(CCc2cc(O)ccc12)C1CCC2(CC1)OCCO2

InChI Key: InChIKey=LTIQSZCATDAGAW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50331315 ((+/-)-3-(1,4-Dioxaspiro[4.5]decan-8-yl)-2,3,4,5-te...) Show SMILES OC1CN(CCc2cc(O)ccc12)C1CCC2(CC1)OCCO2 Show InChI InChI=1S/C18H25NO4/c20-15-1-2-16-13(11-15)5-8-19(12-17(16)21)14-3-6-18(7-4-14)22-9-10-23-18/h1-2,11,14,17,20-21H,3-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from human recombinant NR1-1a/NR2B receptor expressed in mouse L(tk-) cells after 120 mins by scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50331315 ((+/-)-3-(1,4-Dioxaspiro[4.5]decan-8-yl)-2,3,4,5-te...) Show SMILES OC1CN(CCc2cc(O)ccc12)C1CCC2(CC1)OCCO2 Show InChI InChI=1S/C18H25NO4/c20-15-1-2-16-13(11-15)5-8-19(12-17(16)21)14-3-6-18(7-4-14)22-9-10-23-18/h1-2,11,14,17,20-21H,3-10,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor guinea pig brain after 180 mins scintillation counting				Bioorg Med Chem 18: 8005-15 (2010) Article DOI: 10.1016/j.bmc.2010.09.026 BindingDB Entry DOI: 10.7270/Q28W3DJB
					More data for this Ligand-Target Pair