BDBM50331329 CHEMBL1289838::rac-2-(4-(2-chlorophenylsulfonyl)phenyl)-1,1,1-trifluoropropan-2-ol

SMILES: CC(O)(c1ccc(cc1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F

InChI Key: InChIKey=HEYYMMKRFXWVJQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50331329 (CHEMBL1289838 | rac-2-(4-(2-chlorophenylsulfonyl)p...) Show SMILES CC(O)(c1ccc(cc1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C15H12ClF3O3S/c1-14(20,15(17,18)19)10-6-8-11(9-7-10)23(21,22)13-5-3-2-4-12(13)16/h2-9,20H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 transfected in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 7071-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.097 BindingDB Entry DOI: 10.7270/Q21G0MHX
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50331329 (CHEMBL1289838 | rac-2-(4-(2-chlorophenylsulfonyl)p...) Show SMILES CC(O)(c1ccc(cc1)S(=O)(=O)c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C15H12ClF3O3S/c1-14(20,15(17,18)19)10-6-8-11(9-7-10)23(21,22)13-5-3-2-4-12(13)16/h2-9,20H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 by scintillation proximity assay				Bioorg Med Chem Lett 20: 7071-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.097 BindingDB Entry DOI: 10.7270/Q21G0MHX
					More data for this Ligand-Target Pair