BDBM50331368 CHEMBL1290059::N-((3R,4R)-1-isopropyl-4-(3'-(methylsulfonamido)biphenyl-4-yl)pyrrolidin-3-yl)propane-2-sulfonamide

SMILES: CC(C)N1C[C@H](NS(=O)(=O)C(C)C)[C@H](C1)c1ccc(cc1)-c1cccc(NS(C)(=O)=O)c1

InChI Key: InChIKey=XTJHZPUPANMRKY-PKTZIBPZSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50331368 (CHEMBL1290059 | N-((3R,4R)-1-isopropyl-4-(3'-(meth...) Show SMILES CC(C)N1C[C@H](NS(=O)(=O)C(C)C)[C@H](C1)c1ccc(cc1)-c1cccc(NS(C)(=O)=O)c1 |r| Show InChI InChI=1S/C23H33N3O4S2/c1-16(2)26-14-22(23(15-26)25-32(29,30)17(3)4)19-11-9-18(10-12-19)20-7-6-8-21(13-20)24-31(5,27)28/h6-13,16-17,22-25H,14-15H2,1-5H3/t22-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]-dofetilide from human hERG				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50331368 (CHEMBL1290059 | N-((3R,4R)-1-isopropyl-4-(3'-(meth...) Show SMILES CC(C)N1C[C@H](NS(=O)(=O)C(C)C)[C@H](C1)c1ccc(cc1)-c1cccc(NS(C)(=O)=O)c1 |r| Show InChI InChI=1S/C23H33N3O4S2/c1-16(2)26-14-22(23(15-26)25-32(29,30)17(3)4)19-11-9-18(10-12-19)20-7-6-8-21(13-20)24-31(5,27)28/h6-13,16-17,22-25H,14-15H2,1-5H3/t22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Positive modulation of human GluA2 flip receptor by FLIPR assay				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair