BDBM50331372 CHEMBL1290276::N-((3R,4R)-4-(4'-cyanobiphenyl-4-yl)-1-isopropylpyrrolidin-3-yl)propane-2-sulfonamide

SMILES: CC(C)N1C[C@H](NS(=O)(=O)C(C)C)[C@H](C1)c1ccc(cc1)-c1ccc(cc1)C#N

InChI Key: InChIKey=DOWMMZZPMSPEDB-PKTZIBPZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIA2 (Homo sapiens (Human))	BDBM50331372 (CHEMBL1290276 | N-((3R,4R)-4-(4'-cyanobiphenyl-4-y...) Show SMILES CC(C)N1C[C@H](NS(=O)(=O)C(C)C)[C@H](C1)c1ccc(cc1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C23H29N3O2S/c1-16(2)26-14-22(23(15-26)25-29(27,28)17(3)4)21-11-9-20(10-12-21)19-7-5-18(13-24)6-8-19/h5-12,16-17,22-23,25H,14-15H2,1-4H3/t22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Positive modulation of human GluA2 flip receptor by FLIPR assay				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair