BDBM50331377 CHEMBL1290612::N-((3R,4R)-1-methyl-4-(3'-(trifluoromethyl)biphenyl-4-yl)pyrrolidin-3-yl)propane-2-sulfonamide

SMILES: CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=NEXVKNHJGXACAF-UXHICEINSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50331377 (CHEMBL1290612 | N-((3R,4R)-1-methyl-4-(3'-(trifluo...) Show SMILES CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C21H25F3N2O2S/c1-14(2)29(27,28)25-20-13-26(3)12-19(20)16-9-7-15(8-10-16)17-5-4-6-18(11-17)21(22,23)24/h4-11,14,19-20,25H,12-13H2,1-3H3/t19-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]-dofetilide from human hERG				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50331377 (CHEMBL1290612 | N-((3R,4R)-1-methyl-4-(3'-(trifluo...) Show SMILES CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C21H25F3N2O2S/c1-14(2)29(27,28)25-20-13-26(3)12-19(20)16-9-7-15(8-10-16)17-5-4-6-18(11-17)21(22,23)24/h4-11,14,19-20,25H,12-13H2,1-3H3/t19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.94E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Positive modulation of human GluA2 flip receptor by FLIPR assay				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair