BDBM50331379 CHEMBL1290731::N-((3R,4R)-1-methyl-4-(4-(pyridin-3-yl)phenyl)pyrrolidin-3-yl)propane-2-sulfonamide

SMILES: CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccnc1

InChI Key: InChIKey=MLSAGGODNSGYLO-MOPGFXCFSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50331379 (CHEMBL1290731 | N-((3R,4R)-1-methyl-4-(4-(pyridin-...) Show SMILES CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccnc1 |r| Show InChI InChI=1S/C19H25N3O2S/c1-14(2)25(23,24)21-19-13-22(3)12-18(19)16-8-6-15(7-9-16)17-5-4-10-20-11-17/h4-11,14,18-19,21H,12-13H2,1-3H3/t18-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]-dofetilide from human hERG				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50331379 (CHEMBL1290731 | N-((3R,4R)-1-methyl-4-(4-(pyridin-...) Show SMILES CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccnc1 |r| Show InChI InChI=1S/C19H25N3O2S/c1-14(2)25(23,24)21-19-13-22(3)12-18(19)16-8-6-15(7-9-16)17-5-4-10-20-11-17/h4-11,14,18-19,21H,12-13H2,1-3H3/t18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Positive modulation of human GluA2 flip receptor by FLIPR assay				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair