BDBM50331383 CHEMBL1289179::N-((3R,4R)-1-methyl-4-(4-(thiophen-2-yl)phenyl)pyrrolidin-3-yl)propane-2-sulfonamide

SMILES: CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccs1

InChI Key: InChIKey=BXILYZVQYKOJEX-SJORKVTESA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50331383 (CHEMBL1289179 | N-((3R,4R)-1-methyl-4-(4-(thiophen...) Show SMILES CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccs1 |r| Show InChI InChI=1S/C18H24N2O2S2/c1-13(2)24(21,22)19-17-12-20(3)11-16(17)14-6-8-15(9-7-14)18-5-4-10-23-18/h4-10,13,16-17,19H,11-12H2,1-3H3/t16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]-dofetilide from human hERG				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair
GRIA2 (Homo sapiens (Human))	BDBM50331383 (CHEMBL1289179 | N-((3R,4R)-1-methyl-4-(4-(thiophen...) Show SMILES CC(C)S(=O)(=O)N[C@H]1CN(C)C[C@@H]1c1ccc(cc1)-c1cccs1 |r| Show InChI InChI=1S/C18H24N2O2S2/c1-13(2)24(21,22)19-17-12-20(3)11-16(17)14-6-8-15(9-7-14)18-5-4-10-23-18/h4-10,13,16-17,19H,11-12H2,1-3H3/t16-,17+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Positive modulation of human GluA2 flip receptor by FLIPR assay				Bioorg Med Chem Lett 20: 7116-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.062 BindingDB Entry DOI: 10.7270/Q2WQ042G
					More data for this Ligand-Target Pair