BDBM50331755 CHEMBL1288517::methyl 3,5-bis(trifluoromethyl)benzyl((4'-fluoro-5'-isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl)methyl)carbamate

SMILES: COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(ccc1-c1cc(C(C)C)c(F)cc1OC)C(F)(F)F

InChI Key: InChIKey=FGKHLSWPVWXFAR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50331755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50331755 (CHEMBL1288517 | methyl 3,5-bis(trifluoromethyl)ben...) Show SMILES COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(ccc1-c1cc(C(C)C)c(F)cc1OC)C(F)(F)F Show InChI InChI=1S/C29H25F10NO3/c1-15(2)22-11-23(25(42-3)12-24(22)30)21-6-5-18(27(31,32)33)9-17(21)14-40(26(41)43-4)13-16-7-19(28(34,35)36)10-20(8-16)29(37,38)39/h5-12,15H,13-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP-mediated cholesteryl ester transfer activity after 1 hr by fluorescent cholesteryl esters transfer assay				J Med Chem 54: 4880-95 (2011) Article DOI: 10.1021/jm200484c BindingDB Entry DOI: 10.7270/Q2NG4QZ3
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50331755 (CHEMBL1288517 | methyl 3,5-bis(trifluoromethyl)ben...) Show SMILES COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(ccc1-c1cc(C(C)C)c(F)cc1OC)C(F)(F)F Show InChI InChI=1S/C29H25F10NO3/c1-15(2)22-11-23(25(42-3)12-24(22)30)21-6-5-18(27(31,32)33)9-17(21)14-40(26(41)43-4)13-16-7-19(28(34,35)36)10-20(8-16)29(37,38)39/h5-12,15H,13-14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Corp. Curated by ChEMBL					Assay Description Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysis				Bioorg Med Chem Lett 20: 7469-72 (2010) Article DOI: 10.1016/j.bmcl.2010.10.019 BindingDB Entry DOI: 10.7270/Q2FF3SMV
					More data for this Ligand-Target Pair