BDBM50331756 CHEMBL1288518::methyl 3,5-bis(trifluoromethyl)benzyl((2'-methoxy-5'-propyl-4-(trifluoromethyl)biphenyl-2-yl)methyl)carbamate

SMILES: CCCc1ccc(OC)c(c1)-c1ccc(cc1CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)OC)C(F)(F)F

InChI Key: InChIKey=PLFTUTYIBVOTOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50331756 (CHEMBL1288518 | methyl 3,5-bis(trifluoromethyl)ben...) Show SMILES CCCc1ccc(OC)c(c1)-c1ccc(cc1CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)OC)C(F)(F)F Show InChI InChI=1S/C29H26F9NO3/c1-4-5-17-6-9-25(41-2)24(12-17)23-8-7-20(27(30,31)32)13-19(23)16-39(26(40)42-3)15-18-10-21(28(33,34)35)14-22(11-18)29(36,37)38/h6-14H,4-5,15-16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	753	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Corp. Curated by ChEMBL					Assay Description Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysis				Bioorg Med Chem Lett 20: 7469-72 (2010) Article DOI: 10.1016/j.bmcl.2010.10.019 BindingDB Entry DOI: 10.7270/Q2FF3SMV
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