BDBM50331757 CHEMBL1288519::methyl 3,5-bis(trifluoromethyl)benzyl((5'-tert-butyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl)methyl)carbamate

SMILES: COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(ccc1-c1cc(ccc1OC)C(C)(C)C)C(F)(F)F

InChI Key: InChIKey=MKKDOYAKQUWGKD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50331757 (CHEMBL1288519 | methyl 3,5-bis(trifluoromethyl)ben...) Show SMILES COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(ccc1-c1cc(ccc1OC)C(C)(C)C)C(F)(F)F Show InChI InChI=1S/C30H28F9NO3/c1-27(2,3)19-7-9-25(42-4)24(14-19)23-8-6-20(28(31,32)33)12-18(23)16-40(26(41)43-5)15-17-10-21(29(34,35)36)13-22(11-17)30(37,38)39/h6-14H,15-16H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Corp. Curated by ChEMBL					Assay Description Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysis				Bioorg Med Chem Lett 20: 7469-72 (2010) Article DOI: 10.1016/j.bmcl.2010.10.019 BindingDB Entry DOI: 10.7270/Q2FF3SMV
					More data for this Ligand-Target Pair