BDBM50331763 CHEMBL1289088::methyl 3,5-bis(trifluoromethyl)benzyl((5'-isopropyl-2',4-dimethoxybiphenyl-2-yl)methyl)carbamate

SMILES: COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(OC)ccc1-c1cc(ccc1OC)C(C)C

InChI Key: InChIKey=QHSCDWMBCJIQKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50331763 (CHEMBL1289088 | methyl 3,5-bis(trifluoromethyl)ben...) Show SMILES COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(OC)ccc1-c1cc(ccc1OC)C(C)C Show InChI InChI=1S/C29H29F6NO4/c1-17(2)19-6-9-26(39-4)25(13-19)24-8-7-23(38-3)12-20(24)16-36(27(37)40-5)15-18-10-21(28(30,31)32)14-22(11-18)29(33,34)35/h6-14,17H,15-16H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	694	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Corp. Curated by ChEMBL					Assay Description Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysis				Bioorg Med Chem Lett 20: 7469-72 (2010) Article DOI: 10.1016/j.bmcl.2010.10.019 BindingDB Entry DOI: 10.7270/Q2FF3SMV
					More data for this Ligand-Target Pair