BDBM50331765 CHEMBL1289323::methyl 3,5-bis(trifluoromethyl)benzyl((4-chloro-5'-isopropyl-2'-methoxybiphenyl-2-yl)methyl)carbamate

SMILES: COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(Cl)ccc1-c1cc(ccc1OC)C(C)C

InChI Key: InChIKey=QNIDSQKMRKWMRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331765   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50331765 (CHEMBL1289323 | methyl 3,5-bis(trifluoromethyl)ben...) Show SMILES COC(=O)N(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)Cc1cc(Cl)ccc1-c1cc(ccc1OC)C(C)C Show InChI InChI=1S/C28H26ClF6NO3/c1-16(2)18-5-8-25(38-3)24(12-18)23-7-6-22(29)11-19(23)15-36(26(37)39-4)14-17-9-20(27(30,31)32)13-21(10-17)28(33,34)35/h5-13,16H,14-15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp& Dohme Corp. Curated by ChEMBL					Assay Description Inhibition of CETP-mediated neutral lipid transfer by fluorometric analysis				Bioorg Med Chem Lett 20: 7469-72 (2010) Article DOI: 10.1016/j.bmcl.2010.10.019 BindingDB Entry DOI: 10.7270/Q2FF3SMV
					More data for this Ligand-Target Pair