BDBM50331996 1-(4-(4-chlorophenyl)piperazin-1-yl)-2-(pyridin-4-ylmethoxy)ethanone::CHEMBL1289112

SMILES: Clc1ccc(cc1)N1CCN(CC1)C(=O)COCc1ccncc1

InChI Key: InChIKey=VQWLSJSLTOXKEB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50331996   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50331996 (1-(4-(4-chlorophenyl)piperazin-1-yl)-2-(pyridin-4-...) Show SMILES Clc1ccc(cc1)N1CCN(CC1)C(=O)COCc1ccncc1 Show InChI InChI=1S/C18H20ClN3O2/c19-16-1-3-17(4-2-16)21-9-11-22(12-10-21)18(23)14-24-13-15-5-7-20-8-6-15/h1-8H,9-14H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as Ca2+ influx by FLIPR assay				Bioorg Med Chem Lett 20: 7381-4 (2010) Article DOI: 10.1016/j.bmcl.2010.10.036 BindingDB Entry DOI: 10.7270/Q27S7P13
					More data for this Ligand-Target Pair