BDBM50332123 (S)-2-(4-chlorophenyl)-4-(pyrrolidin-2-ylmethylamino)thieno[3,2-c]pyridine-7-carboxamide::CHEMBL1288219

SMILES: NC(=O)c1cnc(NC[C@@H]2CCCN2)c2cc(sc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=DCMSFYRENMMFPF-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332123   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50332123 ((S)-2-(4-chlorophenyl)-4-(pyrrolidin-2-ylmethylami...) Show SMILES NC(=O)c1cnc(NC[C@@H]2CCCN2)c2cc(sc12)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H19ClN4OS/c20-12-5-3-11(4-6-12)16-8-14-17(26-16)15(18(21)25)10-24-19(14)23-9-13-2-1-7-22-13/h3-6,8,10,13,22H,1-2,7,9H2,(H2,21,25)(H,23,24)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of His-tagged CHK1 after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 20: 7216-21 (2010) Article DOI: 10.1016/j.bmcl.2010.10.105 BindingDB Entry DOI: 10.7270/Q2QV3MR6
					More data for this Ligand-Target Pair				3D Structure (docked)