BDBM50332138 (S)-2-(1H-indol-4-yl)-4-(piperidin-3-ylamino)thieno[3,2-c]pyridine-7-carboxamide::CHEMBL1287949

SMILES: NC(=O)c1cnc(N[C@H]2CCCNC2)c2cc(sc12)-c1cccc2[nH]ccc12

InChI Key: InChIKey=UMYQJKFKDGYYNW-LBPRGKRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50332138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50332138 ((S)-2-(1H-indol-4-yl)-4-(piperidin-3-ylamino)thien...) Show SMILES NC(=O)c1cnc(N[C@H]2CCCNC2)c2cc(sc12)-c1cccc2[nH]ccc12 |r| Show InChI InChI=1S/C21H21N5OS/c22-20(27)16-11-25-21(26-12-3-2-7-23-10-12)15-9-18(28-19(15)16)14-4-1-5-17-13(14)6-8-24-17/h1,4-6,8-9,11-12,23-24H,2-3,7,10H2,(H2,22,27)(H,25,26)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of His-tagged CHK1 after 2 hrs by liquid scintillation counting				Bioorg Med Chem Lett 20: 7216-21 (2010) Article DOI: 10.1016/j.bmcl.2010.10.105 BindingDB Entry DOI: 10.7270/Q2QV3MR6
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